Vasopressin
(ADH):
|
Pituitary
Hormone |
|
|
5-10
units |
Give BID to QID
as ADH replacement in Diabetes Insipidus. |
|
|
40 units |
This
is the dose given for V Fib OR pulseless V Tach. If it doesn't work,
you can try the Epinephrine again... Note: the concentration in your
drip is quite dilute... It would take a 400cc bolus at that
concentration.
|
|
|
This
is the dosing we give for vasodilatory shock, usually 0.04 u/min.
Never titrated.
|
0.01-0.04
u/min |
|
|
This
is the indicated range for acute GIB.
|
0.02-0.06
u/min |
|
|
This
dose is for your brain dead patient. It maintains vital organ
perfusion until the time is right...
|
0.5-6.0
u/min |
ADH
is a naturally occurring pituitary hormone that promotes the reabsorption of H20
at the very end of the distal loop of Henle.
It cause vasoconstriction by directly stimulating peripheral smooth
muscle receptors.
Constriction occurs just about everywhere except for where you naturally
want it not to, causing
CPP, cerebral vasodilation,
cerebral O2 delivery, and
blood flow to vital organs, while ¯
cardiac O2 demand.
Besides VF/VT, ADH is also used for nonnephrogenic, nonpsychogenic
diabetes insipidus, and severe GI hemorrhage.
Side
Effects: Arrhythmias, cardiac arrest,
myocardial ischemia, angina, ¯
CO, bronchospasm/constriction, HA, confusion, vertigo, N/V, eructation,
abdominal cramps, diaphoresis, hives, skin pallor, and gangrene.
Contraindicated:
CAD, CHF, asthma, chronic nephritis with nitrogen retention, migraines,
epilepsy, pregnancy, lactation.
|