Labatelol:

Mixed  a & b-blocker

   

 

IVP DOSING

   
10-20 mg

Slow IVP over 2 minutes.  Repeat as needed.  I like this drug, because it works really well (usually)!  Like Hydralazine, if your order says Q4 hours PRN, it probably will not be enough during a 12 hour shift.  You need to keep giving it to your patient until you get the pressure down!  

(or 0.25mg/kg)
   

300 mg

MAX dose.
 

INFUSION DOSING

   

Obviously, if you haven't given a bolus, its going to be at least 5-10 minutes before you see results.

1-4 mg/min
 

Primarily used for acute, severe HTN, Labetalol causes less vasoconstriction and less bronchospasm than Propranolol does, and, it works better than Propranolol in black patients, and has a more rapid effect on BP (keep patient supine during IV administration).  

 

Side Effects: ¯ BP, ventricular arrhythmias, dizziness, diaphoresis, N/V, HA, fatigue, syncope, transient scalp tingling, vivid dreams, and paresthesias.   

 

Contraindicated: Asthma, CHF, 2° or 3° AV block, ¯ HR, ¯ BP, and cardiogenic shock.  Use cautiously in patients with hepatic failure.

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Copyright 2009, Samos Alixopulos, ICU RN