Lidocaine:

Class Ib Antiarrhythmic

   

 

IVP DOSING

   
0.5-1 mg/kg

Slow IVP over 2 minutes.  This is the dose to give for treatment of PVCs.

   
1-1.5 mg/kg

This dose is for the treatment of V Fib & V Tach...  Slow IVP over 2 minutes.  

   

3 mg/kg

MAX bolus dose.
 

INFUSION DOSING

   

If it worked well, politely ask the patient's mom to stop huging you, and start a drip.  Titrate in 1mg increments.  PLUS give another bolus dose with any increase.  Remember, "good luck" has a short half-life...

1-4 mg/min
 

Lidocaine is used for the treatment and prevention of  ventricular arrhythmias associated with VF/VT, AMI, cardiac surgery, and other precipitating events.  It decreases depolarization, automaticity, and tissue excitability in the ventricles, and works diectly in the ischemic areas of the myocardium.  All class I agents require adequate K+ levels, and this is especially true with Lidocaine, as it is even more effect in the presence of a high K+ level.  Hypokalemia needs to be corrected in order for lidocaine to be fully effective.  

 

Side Effects:   Arrhythmias, ¯ BP, ¯ HR, respiratory depression/arrest, and mental status changes.  Monitor serum levels for signs of toxicity, normal is 2-5 mcg/ml.  Initial signs of toxicity may be dizziness, alterated mental status, slurred speach, somnolence, and paresthesias.  Further toxicity can result in seizures and coma.  If toxicity develops, stop the infusion, notify the MD, and give O2.  

 

Contraindicated: in 2° or 3° AV block, hypotension, and Stokes-Adams syndrome.  If pt has liver disease, is over 70yo, or is in CHF or shock, reduce dose/infusion by 50%.

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Copyright 2009, Samos Alixopulos, ICU RN