|
Hydralazine: |
Vasodilator |
|
|
|
IVP DOSING |
| 10-20 mg |
Slow IVP over 2 minutes. Repeat as needed. Some people do not respond well to this. If your order says Q4 hours PRN, this drug probably will not be very helpful. You need to keep giving your patient boluses until you get the pressure down! |
|
300 mg |
MAX daily dose. |
|
IM DOSING |
|
No IV? No problem! Needles are just as fun now as they used to be! Go and get a big giant one... Hmmm, "Z-Track..." sciatic nerves... Yes, its all coming back to me now... |
20-50 mg |
Hydralazine
dramatically increases CO and has very little impact on CVP or PAWP.
Its primary action is strong arteriolar diation by an unknown mechanism.
Hydralazine increases forward stroke volume and decreases the volume of
blood left behind for regurgitation in the presence of valvular disease.
It quickly lowers BP,
and this is its primary IV use.
It is also used in combination with other drugs for CHF.
Side
Effects: ¯
BP,
HR, angina, palpitations, edema, HA, dizziness, N/V, agranulocytopenia,
neutropenia, leukopenia, skin rash, lupus-like syndrome.
Contraindicated:
in CAD and rheumatic heart disease.
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