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- Complications Of Blood Administration |
2, 3 DPG Deficit:
Now
here's something only an ICU nurse would care to think about!
2, 3 DPG basically lowers the affinity for O2 to HGB, without it, those
little truckloads of oxygen would just cruise around and never dump their load.
So when the 2, 3 DPG level is too low, the oxygen doesn't make it to the
cells that need it.
As a unit of blood gets older, the stored RBCs ability to produce this
enzyme diminish.
Clinical signs of this are bright red venous blood (because the HGB is
overly saturated with O2, like with arterial blood), and an increase in SVO2
(-duh).
The fix is too call the blood bank and tell them you want some of the
good stuff (collected in the last 24 hours).
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