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Procainamide: |
Class Ia Antiarrhythmic |
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IVP DOSING |
| 20-30 mg/min |
SLOOOWW IV! Better to lean on the 20mg/min side of the range. Continue to give until: |
| 1). Arrythmias are supressed. | |
| 2). Patient becomes too hypotensive. | |
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3). PR, or QT, or QRS intervals that widen by over 50%. |
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| 17mg/kg | 4). You've reached the MAX dose! |
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INFUSION DOSING |
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This where to ride if the loading doses worked and you didn't reach the maximum of 17 mg/kg... |
1-4 mg/min |
Used
for a wide variety of rhythms, including VF/VT, A fib, VT, and WPW.
It decreases automaticity, conduction velocity, and myocardial
excitability. Its effects result in
a prolonged refractory period, however, procainamide does not prolong the QT
interval to the extent that Quinidine does.
Side Effects: Widening PR, QRS, or QT interval (with their associated arrhythmias), cardiac arrest, hypotention, Altered mentation, Sz, N/V, thrombocytopenia, hemolytic anemia, neutropenia, agranulocytosis, misc skin rash/irritations. lupus-like syndrome.
Contraindicated:
2°
or 3°
AV block, dig toxicity, myasthenia
gravis, torsades, SLE.
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