Dopamine:

Sympathomimetic Chatecholamine

 

DA1 > DA2 > b; ­ dose = a > b > DA

 

INFUSION DOSING

   

This is the starting dose.  Also known by rebelious types and more "experienced" doctors as "Renal dose Dopa" which may be ordered to increase renal perfusion.

2-5 mcg/kg/min
   

This dose is higher than the previous dose (duh).  You get more cardiac contractility in this dosage range.

5-10 mcg/kg/min
   

Now this is the relief you've been waiting for!  Vasoconstriction!  Now you can go pee...

10-20 mcg/kg/min
   

What, you mean the Vasopressin, Levophed, and the upside down cardiac chair position still isn't enough?  Time to change code status...

20-30 mcg/kg/min

 

Used for severe heart failure, cardiogenic shock, and hypotension to improve CO.  It is the precursor of norepinephrine and epinephrine, and directly releases norepinephrine from stores within the heart.

   

Half life: very short, effects end only 5-10 minutes after IV infusion is stopped.

   

Side Effects:  AMI, arrhythmias, HTN, N/V, HA.  Extravasation causes tissue necrosis.

   

Contraindicated: Tachydysrhythmias and HTN.

*If pt. is on MAO inhibitors, you must cut the dose by 1/10th!!!

Dopamine is preferred when there is impaired renal blood flow, such as severe CHF.

Dobutamine is preferred if a pt. is tachycardic, or has ventricular arrhythmias (or ­risk).

« LAST DRUG

NEXT DRUG »

 

Copyright 2009, Samos Alixopulos, ICU RN