Atropine:

Anticholinergic (vagolytic)

   

 
   

Drug of choice for symptomatic Bradycardia...

IVP DOSING

   
0.5-1mg

Give IVP.  Can also give 1-2 mg with 10cc NS via ETT ("where the hell's that IV nurse!?...")  May repeat (try again) in 3 to 5 minutes...

   

2mg

This is the MAX dose... Grab the crash cart and start pacing!
 

OTHER DOSING

   
Mix in 3cc and give via nebulizer for ASTHMA 0.5-2mg
   

Give this amount IVP every 15 to 30 minutes (!) for organophosphate poisoning, or Carbamate insecticide poisoning until VS improve.  Forget about your other patients for awhile...

2-5mg
   

Atropine inhibits acetylcholine and blocks its vagal effects on the SA and AV nodes, allowing for improved conduction and increased HR.  It also reverses cholinergic mediated decreases in HR, BP, and SVR.

   

Side Effects: HR, VT/VF, HA, anxiety, altered psych/mental states, visual changes, dilated pupils, IOP,  dry mouth, N/V, urine retention, and impotence.  

   

Contraindicated: in patients with tachycardia, myocardial ischemia, acute hemorrhage, asthma, myasthenia gravis, and glaucoma.

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Copyright 2009, Samos Alixopulos, ICU RN